NOXXON Pharma N.V. (Euronext Growth Paris: ALNOX) (Paris:ALNOX), a biotechnology company focused on improving cancer treatments by targeting the tumor microenvironment (TME), announced today its financial results for the fiscal year ending December 31, 2020. NOXXON Pharma N.V. Aram Mangasarian, Ph.D., Président Directeur Général Tél. Personnel expenses included non-cash share-based payment expenses amounting to €51 thousand in 2020 and €53 thousand in 2019. These are described as forward-looking statements. zeit aktuelle nachrichten; 30.04. noxxon pharma n.v.: noxxon gibt 1,2 mio. Importantly, no warrants or other option-like instruments were attached to the shares issued in these financings. On December 31, 2019, a significant number of warrants linked to previous financings, that are subject to anti-dilution adjustments affecting exercise price and number of shares issued, were outstanding. In both, Fiscal Year 2020 (FY 2020) and Fiscal Year 2019 (FY 2019), NOXXON did not generate any revenues. L’approbation du DSMB de poursuivre cette étude fait suite à l'évaluation des données de sécurité stipulée dans le protocole de l'étude, et qui devait être menée après que les trois patients de la troisième et dernière cohorte aient atteint au moins quatre semaines de traitement par la dose la plus élevée. 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On top of the combination therapy of NOX-A12 plus anti-PD-1, the study will test two different standard of care chemotherapy treatments in second-line patients. +49 (0) 172 861 8540 and +49 (0) 175 804 1816 Pre-clinical work comparing combination strategies for NOX-E36 in solid tumors to identify the most promising approaches are also advancing. NOXXON's Key Financial Figures for Fiscal Year 2020 Compared to the Same Period in 2019, Net loss attributable to owners of the company, Net loss attributable to non-controlling interest, NOXXON's oncology-focused pipeline acts on the tumor microenvironment (TME) and the cancer immunity cycle by breaking the tumor protection barrier and blocking tumor repair. With encouraging data from a previous study and with guidance of the SAB, NOXXON is preparing to initiate a two-arm clinical trial in pancreatic cancer. Manufacturing Drug Supply Tel. One of the most interesting aspects of final top-line data, published by Prof. Niels Halama at the European Society for Medical Oncology (ESMO) Congress in September 2020, was the updated overall survival data showing that three patients, including two receiving their fourth line of therapy for metastatic pancreatic cancer, had lived more than one year and one of them living for almost two years. View source version on businesswire.com: https://www.businesswire.com/news/home/20210428005849/en/, NOXXON Pharma N.V. Aram Mangasarian, Ph.D., Chief Executive Officer Max 1Mo. In February 2021, NOXXON appointed a Scientific Advisory Board (SAB) under the chairmanship of Dr. Jose Saro. NOXXON GIBT FREIGABE DER HÖCHSTEN DOSIS VON NOX-A12 IN DER PHASE-1/2-GEHIRNTUMORSTUDIE DURCH DAS DATA SAFETY MONITORING BOARD BEKANNT Berlin, Deutschland, 10. Finance income of €406 thousand resulted from the derecognition of conversion rights in connection with the ASO financing upon conversion of the bonds and of €12 thousand relating to the cashless exercise of warrants. business wire: noxxon pharma: das data safety monitoring board bestÄtigt sicherheit und gibt zustimmung zur weiteren patientenrekrutierung in … Cash secured in 2020 and 2021 combined with the available convertible bond financing vehicle has extended NOXXON's financial visibility to Q2 2022. The company completed recruitment of patients into the last of the three planned cohorts in April 2021. Other operating income decreased from €279 thousand in FY 2019 to €147 thousand in FY 2020. With its improved finances, NOXXON plans to restart clinical trials with NOX-E36. +49 (0) 30 726247 0 Plus d’informations sont disponibles sur : www.noxxon.com. Personnel expenses included non-cash share-based payment expenses amounting to €111 thousand in 2020 and €54 thousand in 2019. Tel. noxxon pharma: das data safety monitoring board bestÄtigt sicherheit und gibt zustimmung zur weiteren patientenrekrutierung in die letzte hochdosis-kohorte der nox-a12 phase-1/2-gehirntumorstudie Certain statements in this communication contain formulations or terms referring to the future or future developments, as well as negations of such formulations or terms, or similar terminology. In the second part of the study, when NOX-A12 was then combined with Merck's anti-PD-1 immunotherapeutic antibody, Keytruda, 25% of patients achieved stable disease according to the iRECIST criteria, despite only 5% having any response to their prior anti-cancer treatment before entering the NOXXON clinical trial. As a result of the above factors, the Group's loss before income tax increased by €9,546 thousand from €860 thousand in FY 2019 to €10,406 thousand in FY 2020 (thereof loss from operations amounting to €5,769 thousand in FY 2020 vs. €3,948 thousand in FY 2019, resulting in an operating cash outflow of €5,224 thousand in FY 2020 vs. €4,286 thousand in FY 2019). This mechanism allows NOX-A12 to stimulate an increased immune response within the tumor, making the tumor microenvironment immunologically "hotter". NOXXON ANNOUNCES DATA SAFETY MONITORING BOARD VALIDATES NOX-A12 HIGHEST DOSE IN PHASE 1/2 BRAIN CANCER TRIAL Berlin, Germany, May 10, 2021, 06.00 p.m. CEST -NOXXON Pharma N.V. (Euronext Growth Paris: ALNOX), a biotechnology company focused on improving cancer treatments by targeting the tumor microenvironment (TME), announced today that an independent … Income tax expenses decreased to nil in FY 2020 from €1 thousand in FY 2019. These financings combined with the potential of the ASO vehicle have extended the financial visibility to Q2 2022. eur kapitalerhÖhung durch wandlung von aktienoptionsscheinen durch kreos capital und andere bestehende investoren bekannt It is NOXXON's key priority to ensure timely completion of the ongoing Phase 1/2 dose escalation trial and present top-line data in 2021. Preliminary data from the first dose group showed tumor reductions in all three patients, with one patient achieving a durable longer than four months objective response (tumor volume reduction of >50%). This strategic approach will enable NOXXON to choose the optimal regimen to move forward into a randomized, controlled pivotal study targeting market authorization application in 2026 and approval in 2027.

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